Timothy J. Garrett
Associate Professor
Research Focus
The research in Garrett’s lab involves the application and development of mass spectrometry for clinical research covering many areas such as cancer, the microbiome, rare diseases, and autoimmune disorders. This diversity in research is enabled because of the flexibility that mass spectrometry offers. A significant area of research focuses on the development of metabolomics and lipidomics. The metabolome encompasses the entire set of small molecules that may be found in a biological specimen. It consists of intermediates, conjugates, hormones, and even exogenous metabolites from food or the environment that have an impact on health (the exposome). Metabolomics refers to the measurement of these metabolites typically involving mass spectrometry.
Education and Training
2001–2006: Ph.D. Analytical Chemistry, University of Florida (lab of Richard Yost)
1995–1999: Bachelor’s in Chemistry, University of Georgia
Selected Awards
COM Exemplary Teacher Award (2019, 2024)
UF Term Professorship (2018)
Selected Activities
Co-Editor-in-Chief, Journal of Mass Spectrometry and Advances in the Clinical Lab 2022–present
Director, Southeast Center for Integrated Metabolomics, 2017–present
Chief, Experimental Pathology, 2019–present
Selected Publications
Christopher MW, Klug AC, Lee JH, Ericson AC, Bazargani SF, Dinglasan RR, Prentice BM, Garrett TJ. Indole-3-pyruvate: Analysis and Control of Tautomerism and Reactivity. Anal. Chem., 2024, 96, 10399–10407.
Li W, Chace DH, Garrett TJ. Quantitation of phenylalanine and tyrosine from dried Blood/Plasma spots with impregnated stable isotope internal standards (SIIS) by FIA-SRM. Clin. Chim. Acta. 2023, 549:117551.
Garrett TJ, Coatsworth H, Mahmud I, Hamerly T, Stephenson CJ, Ayers JB, Yazd HS, Miller MR, Lednicky JA, Dinglasan RR. Niclosamide as a chemical probe for analyzing SARS-CoV-2 modulation of host cell lipid metabolism. Front. Microbiol. 2023, 14:1251065.