Daniel Seidel
Katritzky Term Professor in Heterocyclic Chemistry
Research Focus
The Seidel Group develops new methods in synthetic organic chemistry with a focus on C–H bond functionalization, asymmetric catalysis, and the rapid construction of molecular complexity from simple building blocks. Their research emphasizes efficiency, sustainability, and minimal use of protecting groups. This enables the streamlined synthesis of complex, bioactive molecules, particularly nitrogen-containing heterocycles that are important in pharmaceuticals and materials science.
Education and Training
2002–2005: Postdoc, Harvard University (lab of D. A. Evans)
1998–2002: Ph.D. Chemistry, University of Texas at Austin (lab of J. L. Sessler)
1993–1998: Diplom, Friedrich-Schiller-Universität Jena, Germany
Selected Awards
Novartis Chemistry Lectureship (2017)
Japanese Society for the Promotion of Science (JSPS) Fellow (2014)
Humboldt Research Fellowship for Experienced Researchers (2013)
Amgen Young Investigator Award (2011)
Alfred P. Sloan Research Fellowship (2011)
Selected Activities
Co-organizer of the biennial Florida Heterocyclic and Synthetic Chemistry Conference (FloHet)
Selected Publications
Kamal Bhatt, Alafate Adili, Andrew H. Tran, Kamal M. Elmallah, Ion Ghiviriga, and Daniel Seidel. Photocatalytic Decarboxylative Alkylation of Cyclic Imine-BF3 Complexes: A Modular Route to Functionalized. J. Am. Chem. Soc. 2024, 146, 26331–26339.
Zhengbo Zhu, Minami Odagi, Nantamon Supantanapong, Weici Xu, Jaan Saame, Helmi-Ulrika Kirm, Khalil A. Abboud, Ivo Leito, and Daniel Seidel. Modular Design of Chiral Conjugate-Base-Stabilized Carboxylic Acids: Catalytic Enantioselective [4+2] Cycloadditions of Acetals. J. Am. Chem. Soc. 2020, 142, 15252−15258.
Weijie Chen, Anirudra Paul, Khalil A. Abboud, and Daniel Seidel. Rapid Functionalization of Multiple C–H Bonds in Unprotected Alicyclic Amines. Nat. Chem. 2020, 12, 545–550.