Fan Hong
Assistant Professor
Research Focus
The mission of the Hong Lab is to develop (1) next-generation bioanalytical methods for accurate diagnostics and disease mechanisms and (2) new therapeutic approaches with cell and biomolecular engineering. Our main areas of focus are DNA advanced fluorescence imaging for spatial omics, mRNA therapeutics, gene regulation, and nucleic acid self-assembly.
Education and Training
2019–2023: Postdoc, Harvard Medical School and Harvard University (lab of Peng Yin)
2014–2019: Ph.D. Chemistry, Arizona State University (labs of Hao Yan, Alexander A. Green, and Petr Sulc)
2010–2014: B.S. Chemistry, Huazhong University of Science and Technology
Selected Awards
McKnight Brain Institute Accelerator Award (2025)
The Robert Dirks Molecular Programming Prize (2024)
Harvard Chinese Life Science Distinguished Research Award (2020)
Selected Publications
Fan Hong, Jocelyn Y Kishi, Jiyoun Jeong, Sinem K. Saka, Hanquan Su, Peng Yin. Thermal-plex: Fluidic-free, rapid sequential multiplexed imaging with DNA encoded thermal channels. Nature Methods, 2024, 21, 331-341.
Fan Hong, Duo Ma, Kaiyue Wu, Lida A. Mina, Rebecca C. Luiten, Yan Liu, Hao Yan*, Alexander A. Green*. Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators, Cell, 2020, 180, 1018–1032.
Fan Hong, John Shreck, Petr Sulc, Understanding DNA interactions in crowded environments with a coarse-grained model, Nucleic Acid Research, 2020, 48, 10726–10738.