Sandra Loesgen
Associate Professor
Research Focus
The research goals of the Loesgen Lab are to (i) discover the role of microbial nature products (NPs) in complex ecosystems, (ii) elucidate the structure of NPs and assess their potential for human health applications and biochemical research, and (iii) to decipher the chemical determinants of microbe-host interactions.
Education and Training
2011–2013: Postdoc, National Institutes of Health, Bethesda, MD (lab of Carol Bewley)
2008–2010: Postdoc, Scripps Institution of Oceanography, UCSD, La Jolla, CA (lab of Bill Fenical)
2000–2007: Ph.D. Chemistry, Georg-August University of Göttingen, Germany (lab of Axel Zeeck)
Selected Awards
ASP Matt Suffness (2023)
JNP Jack L. Beal award (2020)
Selected Activities
Associate Editor, Mycologia
ASP Executive Committee Member (2025–2029)
Advisory Board for Natural Products Reports ACS National Award Selection Committee (2024–2026 cycle)
ACS Postdoc to Faculty Workshop
Selected Publications
P. E. Mandelare, S. S. Yee, D. G. Icenhour, E. N. Kaweesa, M. McCauley, A. L. Risinger, J. D. Rudolf, S. Loesgen.* Chemical Diversity of Aspergillus alliaceus Phenotypes: Discovery of brominated Bianthrones with triple-negative breast cancer Activity. ChemBioChem 2024 e202400398.
M. McCauley, T. L. Goulet, C. R. Jackson, S. Loesgen*. Systematic review of cnidarian microbiomes reveals insights into the structure, specificity, and fidelity of marine associations. Nat. Commun. 2023, 14, 4899.
C. Zhu, B. Xu, D. A. Adpressa, J. D. Rudolf*, S. Loesgen.* Discovery and biosynthesis of a structurally dynamic antibacterial diterpenoid. Angewandte Chemie 2021, 60, 14163-14170.