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College of Liberal Arts and Sciences University of Florida
Faculty Member UF Department of Chemistry

UF Department of Chemistry

Leigh Hall 312

352-392-9700

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Simon Enrique Lopez D’Sola

Assistant Instructional Professor

Teaching Focus

Teaching: General Chemistry I (CHM2045), General Chemistry II (CHM2045), General Chemistry Labs (CHM2045L & CHM2046L), Organic Chemistry I (CHM2210) .

Research Focus (with Undergraduate students): Organofluorine Chemistry, Medicinal Chemistry (Neglected Tropical Diseases).

Education and Training

2014: Visiting Professor, Organofluorine Chemistry (lab of Bill Dolbier, University of Florida).

2010: Visiting Professor, C-H activation chemistry (lab of E. van der Eyken, KU Leuven, Belgium)

2003–2004: Visiting Professor, synthesis of heterocycles (V. Snieckus Research Group. Queen’s University, Kingston, ON, Canada)

1990–1997: Doctor in Medicinal Chemistry (Universidad Central, Caracas, Venezuela)

1985–1990: Pharmacist (Universidad Santa Maria, Caracas, Venezuela)

Selected Awards

National Prize in Science, Technology and Innovation to the best published research paper, National Ministry for Science, Technology and Innovation, Venezuela (2017)

Anderson scholar, University of Florida (Academic year 2018–2019)

Selected Activities

Invited (Guest) Editor, special number “Current Organic Synthesis”: Current Organic Synthesis, Volume 7, Number 5, October 2010: The Trifluoromethyl Group in Organic Synthesis: Recent Developments

Selected Publications

Romero, A.H.; Medina, R.; Alcalá, A.; García, Y.; Núñez, J.; Leañez, J.; Serrano-Martín, X.; López, S.E. Design, synthesis, structure-activity relationship and mechanism of action studies of a series of chloro-1-phthalazinyl hydrazones as potent agents against Leishmania braziliensis. Eur. J. Med. Chem. 2017, 127, 606–620.

Rubinski, M.A.; Lopez, S.E.; Dolbier, W.R. Jr. Direct Access to 2-Difluoromethyl Indoles via Photoredox Catalysis. J. Fluorine Chem., 2019, 224, 80–88.

López, S.E.; Mitani, A.; Pena, P.; Ghiviriga, I.; Dolbier, W.R. Jr. Use of 1-pentafluorosulfanyl-phenylacetylenes for the preparation of SF5-substituted five-membered ring heterocycles through 1,3-dipolar cycloadditions. Isoxazoles and isoxazolines. J. Fluorine Chem. 2015, 176, 121-126.